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Pregabalin ≥99% — pure substance
16,19 PLN
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Pregabalin – Laboratory Reagent, CAS 148553-50-8
WARNING: Chemical reagent intended solely for laboratory, research and analytical purposes. NOT FOR HUMAN OR ANIMAL CONSUMPTION. It is not a medicinal product, dietary supplement or food.
Pregabalin is an organic compound belonging to the family of γ-aminobutyric acid (GABA) derivatives, formally (S)-3-(aminomethyl)-5-methylhexanoic acid. Structurally it is an analogue of GABA bearing a branched aliphatic side chain, which gives it physicochemical and receptor-binding characteristics distinct from the parent neurotransmitter. As a single (S)-enantiomer it is a frequent subject of medicinal-chemistry research, experimental pharmacology and instrumental analysis. In the laboratory it typically presents as a white crystalline powder that is freely soluble in water as well as in acidic and basic aqueous solutions, which simplifies the preparation of standard solutions.
Physicochemical Data
| IUPAC Name | (3S)-3-(aminomethyl)-5-methylhexanoic acid |
| Synonyms | Pregabalin, (S)-isobutyl-GABA, (S)-3-(aminomethyl)-5-methylhexanoic acid, CI-1008, PD-144723 |
| CAS Number | 148553-50-8 |
| Molecular Formula | C8H17NO2 |
| Molar Mass | 159.23 g/mol |
| Appearance | white to off-white crystalline powder |
| Solubility | freely soluble in water and in acidic and basic aqueous solutions |
| Melting Point | approx. 194–196 °C |
| Boiling Point | no reliable data / under review (decomposes before boiling) |
| Purity | ≥99% |
Research Applications
In a scientific context, pregabalin serves as a reference compound and analytical standard in studies of ligands targeting the α2δ subunit of voltage-gated calcium channels. It is used in structure–activity relationship (SAR) research, stereoselective chemistry and enantiomer-separation methodology. In analytical laboratories it functions as a reference substance for validating HPLC, LC-MS, NMR and IR methods. It also provides a convenient starting point for the synthesis of derivatives and the study of metabolites. Owing to its high aqueous solubility it is a practical model for investigating the physicochemical behaviour of amino-acid-like zwitterions. This product is supplied strictly for research use and is not intended for diagnostic or therapeutic purposes.
Store in a tightly closed container in a dry, cool place, away from light and moisture, in line with good laboratory practice.
BRM-PREG
Pregabalin ≥99% — chemical reagent for laboratory, research and analytical use. Not for human or animal consumption.
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