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SLU-PP-332 (SLU-SENSIA) — research solution 18 mg/18 ml in DMSO (1 mg/ml), ≥98%
226.79 PLN
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SLU-PP-332
WARNING: Chemical reagent intended solely for laboratory, research and analytical purposes. NOT FOR HUMAN OR ANIMAL CONSUMPTION. It is not a medicinal product, dietary supplement or food.
SLU-PP-332 is a research compound described in the scientific literature as an agonist of the ERR receptors (estrogen-related receptors). The ERR receptors (ERRα, ERRβ, ERRγ) belong to the orphan nuclear receptor superfamily and are the subject of intensive research into energy metabolism, mitochondrial biogenesis and skeletal-muscle function. SLU-PP-332 appears in peer-reviewed literature as a pharmacological tool compound used to probe the activity of this receptor family in experimental models.
The material is supplied as a ready-made solution in DMSO, not as a powder: 18 mg of SLU-PP-332 dissolved in 18 ml of dimethyl sulfoxide, i.e. a concentration of 1.0 mg/ml (approx. 3.44 mmol/l). The chemical identity of the reagent has been confirmed against PubChem record CID 5338394 (CAS number 303760-60-3); the parameters in the table below are taken from that record. The purity of the base substance declared by the manufacturer is ≥ 98%; instrumental assay results for a specific shipment are stated in the Certificate of Analysis.
Physicochemical data
| Systematic name (IUPAC) | 4-hydroxy-N-[(E)-naphthalen-2-ylmethylideneamino]benzamide |
| Equivalent name | (E)-4-hydroxy-N′-(naphthalen-2-ylmethylene)benzohydrazide |
| Trade name | SLU-SENSIA (NONSENSIA brand) — the same compound, CAS 303760-60-3 |
| Synonyms | SLU-PP-332; PP-332; ERR agonist (pan-ERR) |
| CAS number | 303760-60-3 |
| Molecular formula | C18H14N2O2 |
| Molar mass | 290.3 g·mol−1 (monoisotopic mass 290.1055 Da) |
| Structural class | aroylhydrazone (benzoic acid hydrazone) — a small molecule, not a peptide |
| Isomerism | no stereogenic centre; the only isomerism is the C=N bond geometry — the material supplied is the (E) isomer |
| InChIKey | RNZIMBFHRXYRLL-XDHOZWIPSA-N |
| SMILES (isomeric) | C1=CC=C2C=C(C=CC2=C1)/C=N/NC(=O)C3=CC=C(C=C3)O |
| Database identifiers | PubChem CID 5338394 · ChEMBL CHEMBL4208749 |
| Computed properties (PubChem) | XLogP 3.7 · TPSA 61.7 Å2 · H-bond donors/acceptors 2/3 · rotatable bonds 3 |
| Form supplied | clear to slightly yellow liquid solution (not a powder) |
| Package contents | 18 mg SLU-PP-332 in 18 ml DMSO — mass concentration 1.0 mg/ml, molar concentration approx. 3.44 mmol/l (3.44 mM) |
| Solvent | dimethyl sulfoxide (DMSO), analytical grade, ≥ 99.9% |
| Packaging | glass vial with a screw cap, wrapped in light-protective film; packed in Poland |
| Purity of the base substance | ≥ 98% (manufacturer declaration) |
| Storage | cool, dry, protected from light, in the originally closed bottle; DMSO is hygroscopic — limit exposure to moisture and avoid repeated freeze-thaw cycles |
Characteristics and research application
SLU-PP-332 is used in basic research as an agonist of the ERR receptors — a class of nuclear receptors that regulate the expression of genes involved in oxidative metabolism, mitochondrial function and cellular energy balance. In the scientific literature this compound is indicated as a research tool for analysing ERR-dependent signalling pathways in in vitro and preclinical in vivo models, conducted exclusively under laboratory conditions.
The product is offered as a compound for advanced laboratory research, intended for reference work, validation of analytical methods and experiments carried out by qualified personnel. Because it is a relatively new research reagent with a limited set of widely available, confirmed physicochemical data, independent verification of the identity and purity of the material by instrumental methods (NMR, LC-MS, HPLC) on the basis of the Certificate of Analysis supplied with the given batch is strongly recommended.
The reagent is not intended for diagnostic, therapeutic or consumer use. Responsibility for the lawful and safe use of the substance rests with the purchaser acting as a research entity.
BRM-SLU
SLU-PP-332 / SLU-SENSIA — research solution 18 mg in 18 ml DMSO (1.0 mg/ml), CAS 303760-60-3, C18H14N2O2, base substance purity ≥ 98%. For laboratory, research and analytical use only. Not for human or animal consumption.
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